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Selectin

Autor:	Lambert M. Surhone / Miriam T. Timpledon / Susan F. Marseken
Verfügbarkeit:	Auf Lager.
Artikelnummer:	624580
ISBN / EAN:	9786131080791

Verfügbarkeit: sofort lieferbar

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High Quality Content by WIKIPEDIA articles! Selectins are a family of cell adhesion molecules (or CAMs). All selectins are single-chain transmembrane glycoproteins that share similar properties to C-type lectins due to a related amino terminus and calcium-dependent binding. Selectins bind to sugar moieties and so are considered to be a type of lectin, cell adhesion proteins that bind sugar polymers.The name selectin comes from the words "selected" and "lectins," which are a type of carbohydrate-recognizing proteins.During an inflammatory response, stimuli such as histamine and thrombin cause endothelial cells to mobilize P-selectin from stores inside the cell to the cell surface. In addition, cytokines such as TNF-alpha stimulate the expression of E-selectin and additional P-selectin a few hours later.